NIR Absorbing Dyes For Photo Acoustic Imaging

Near infrared absorbing dyes improve penetration depth in photoacoustic imaging through decreased light scattering.

Akita NIR dye characteristics:
-High absorbance at 750-870 nm, minimal emission
-Strong photoacoustic response
-Photostable
-Conjugatable to biomolecules for targeted tissue imaging

NIR dyes available for purchase and relevant characteristics

Catalog #	Price	Solubility	λ_max, log(ε)	Conjugating group*
NIR-001	1 mg: $500 10 mg: $2000 100 mg: $10000	Organic	Toluene: 873 nm, 5.45	NHS ester
NIR-002	1 mg: $500 10 mg: $2000 100 mg: $15000	Amphiphilic	Ethanol: 858 nm, 5.30 Water: 855 nm, 4.78	NHS ester
NIR-003	1 mg: $500 10 mg: $2000 100 mg: $10000	Organic	DMSO: 759 nm, 5.18	Primary amine

*-Incorporation of alternate conjugating groups is available as custom synthesis

Catalog #: NIR-001
Price: 1 mg: $500 10 mg: $2000 | 100 mg: $10000
Solubility: Organic
λ_max, log(ε): Toluene: 873 nm, 5.45
Conjugating group*: NHS ester

Catalog #: NIR-002
Price: 1 mg: $500 10 mg: $2000 | 100 mg: $15000
Solubility: Amphiphilic
λ_max, log(ε): Ethanol: 858 nm, 5.30 Water: 855 nm, 4.78
Conjugating group*: NHS ester

Catalog #: NIR-003
Price: 1 mg: $500 10 mg: $2000 | 100 mg: $10000
Solubility: Organic
λ_max, log(ε): DMSO: 759 nm, 5.18
Conjugating group*: Primary amine

Literature:Bardon, K. M. et al., “Synthesis of Water-Soluble Far-Red-Emitting Amphiphilic BODIPY Dyes,” ACS Omega, 3, 2018, 13195-13199